Jessner's Solution with Trichloroacetic Acid Chemical Peel: Optimizing Outcomes and Safety

Plast Reconstr Surg Glob Open. 2019 May 17;7(5):e2250. doi: 10.1097/GOX.0000000000002250. eCollection 2019 May.

Abstract

Trichloroacetic acid (TCA) is a versatile agent, efficacious in treating a spectrum of facial rhytids and dyschrommias at varying concentrations. TCA is commonly used in a 30%-35% concentration to achieve a medium-depth peel into the upper reticular dermis. The addition of Jessner's solution before the TCA peel application leads to partial removal of epidermis, allowing for deeper penetration of the TCA. This combination is beneficial, as lower concentrations of TCA can be used for the same depth of peel, minimizing complications such as scarring.