Ultrasonographic assessment of femoral cartilage thickness in patients with and without uveitis in Behçet's disease

Rheumatol Int. 2020 Jan;40(1):75-80. doi: 10.1007/s00296-019-04361-1. Epub 2019 Jul 23.

Abstract

The objective for this study is to evaluate the femoral cartilage thickness in patients with/without uveitis in Behçet's disease (BD). Patients with BD aged 18-70 years were included. The demographic and clinical characteristics of the patients were recorded. The thickness of femoral articular cartilage was measured with musculoskeletal ultrasound. Cartilage thickness was measured bilaterally from the central points of medial condyle (MFC), lateral condyle (LFC), and intercondylar area (ICA). 20 patients with uveitis [uveitis (+)] and 20 patients without uveitis [uveitis (-)] were included. Both right and left MFC and LFC had statistically significant thinner cartilage in uveitis (+) group (p < 0.05). For the ICA, uveitis (+) patients had thinner femoral cartilage than uveitis (-) patients; however, in the left side, statistically significance could not be detected. Femoral cartilage was thinner in uveitis (+) patients than in uveitis (-) patients in BD. This relationship between uveitis and femoral cartilage thickness may be helpful in the prevention and early treatment of cartilage degeneration.

Keywords: Behçet’s disease; Femoral cartilage; Ultrasonography; Uveitis.

MeSH terms

  • Adult
  • Arthritis / diagnostic imaging
  • Arthritis / physiopathology*
  • Behcet Syndrome / diagnostic imaging
  • Behcet Syndrome / physiopathology*
  • Cartilage, Articular / diagnostic imaging*
  • Cartilage, Articular / pathology
  • Case-Control Studies
  • Female
  • Femur / diagnostic imaging*
  • Humans
  • Knee Joint / diagnostic imaging*
  • Male
  • Middle Aged
  • Organ Size
  • Ultrasonography
  • Uveitis / physiopathology*
  • Young Adult