HTLV 1/2 Prevalence and risk factors in individuals with HIV/AIDS in Pernambuco, Brazil

Rev Soc Bras Med Trop. 2019 Jul 18:52:e20180244. doi: 10.1590/0037-8682-0244-2018.

Abstract

Introduction: Apart from masking the diagnosis of AIDS in patients with HIV/AIDS, human T-cell lymphotropic virus (HTLV), when present, also increases the risk of myelopathies and neurological disease in these patients.

Methods: Disease prevalence was estimated by ELISA and confirmed by Western blot.

Results: The coinfection rate was 1.5% (11/720); 10 of 11 patients had HTLV-1, and the remaining one had HTLV-2. The majority were male, over 40 years old, and of pardo color (ethnicity).

Conclusions: There was no association between the risk factors examined and HTLV/HIV coinfection. This is the first study to report the occurrence of HTLV-2 in Pernambuco.

MeSH terms

  • Adolescent
  • Adult
  • Blotting, Western
  • Brazil / epidemiology
  • Coinfection*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • HIV Infections / complications*
  • HIV Infections / epidemiology
  • HTLV-I Infections / complications*
  • HTLV-I Infections / epidemiology
  • HTLV-II Infections / complications*
  • HTLV-II Infections / epidemiology
  • Human T-lymphotropic virus 1
  • Human T-lymphotropic virus 2
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Risk Factors
  • Socioeconomic Factors
  • Young Adult