Suicide Risk in Bipolar Disorder: A Brief Review

doi:10.3390/medicina55080403

Review

. 2019 Jul 24;55(8):403.

doi: 10.3390/medicina55080403.

Suicide Risk in Bipolar Disorder: A Brief Review

Peter Dome^{1

2}, Zoltan Rihmer^{3

4}, Xenia Gonda^{3

4

5

6}

Affiliations

¹ Department of Psychiatry and Psychotherapy, Semmelweis University, Faculty of Medicine, 1125 Budapest, Hungary. dome_peter@yahoo.co.uk.
² National Institute of Psychiatry and Addictions, Laboratory for Suicide Research and Prevention, 1135 Budapest, Hungary. dome_peter@yahoo.co.uk.
³ Department of Psychiatry and Psychotherapy, Semmelweis University, Faculty of Medicine, 1125 Budapest, Hungary.
⁴ National Institute of Psychiatry and Addictions, Laboratory for Suicide Research and Prevention, 1135 Budapest, Hungary.
⁵ MTA-SE Neuropsychopharmacology, Neurochemistry Research Group, Hungarian Academy of Sciences, 1089 Budapest, Hungary.
⁶ NAP-2-SE New Antidepressant Target Research Group, Hungarian Brain Research Program, Semmelweis University, 1089 Budapest, Hungary.

PMID: 31344941
PMCID: PMC6723289
DOI: 10.3390/medicina55080403

Free PMC article

Review

Suicide Risk in Bipolar Disorder: A Brief Review

Peter Dome et al. Medicina (Kaunas). 2019.

Free PMC article

. 2019 Jul 24;55(8):403.

doi: 10.3390/medicina55080403.

Authors

Peter Dome^{1

2}, Zoltan Rihmer^{3

4}, Xenia Gonda^{3

4

5

6}

Affiliations

¹ Department of Psychiatry and Psychotherapy, Semmelweis University, Faculty of Medicine, 1125 Budapest, Hungary. dome_peter@yahoo.co.uk.
² National Institute of Psychiatry and Addictions, Laboratory for Suicide Research and Prevention, 1135 Budapest, Hungary. dome_peter@yahoo.co.uk.
³ Department of Psychiatry and Psychotherapy, Semmelweis University, Faculty of Medicine, 1125 Budapest, Hungary.
⁴ National Institute of Psychiatry and Addictions, Laboratory for Suicide Research and Prevention, 1135 Budapest, Hungary.
⁵ MTA-SE Neuropsychopharmacology, Neurochemistry Research Group, Hungarian Academy of Sciences, 1089 Budapest, Hungary.
⁶ NAP-2-SE New Antidepressant Target Research Group, Hungarian Brain Research Program, Semmelweis University, 1089 Budapest, Hungary.

PMID: 31344941
PMCID: PMC6723289
DOI: 10.3390/medicina55080403

Abstract

Bipolar disorders (BDs) are prevalent mental health illnesses that affect about 1-5% of the total population, have a chronic course and are associated with a markedly elevated premature mortality. One of the contributors for the decreased life expectancy in BD is suicide. Accordingly, the rate of suicide among BD patients is approximately 10-30 times higher than the corresponding rate in the general population. Extant research found that up to 20% of (mostly untreated) BD subjects end their life by suicide, and 20-60% of them attempt suicide at least one in their lifetime. In our paper we briefly recapitulate the current knowledge on the epidemiological aspects of suicide in BD as well as factors associated with suicidal risk in BD. Furthermore, we also discuss concisely the possible means of suicide prevention in BD.

Keywords: bipolar disorder; mood disorders; mortality; suicidal; suicide.

Conflict of interest statement

The authors declare no conflict of interest.

Cited by

Esketamine and Psilocybin-The Comparison of Two Mind-Altering Agents in Depression Treatment: Systematic Review.
Psiuk D, Nowak EM, Dycha N, Łopuszańska U, Kurzepa J, Samardakiewicz M. Psiuk D, et al. Int J Mol Sci. 2022 Sep 28;23(19):11450. doi: 10.3390/ijms231911450. Int J Mol Sci. 2022. PMID: 36232748 Free PMC article. Review.
Mathematical Model of Interaction of Therapist and Patients with Bipolar Disorder: A Systematic Literature Review.
Nursuprianah I, Anggriani N, Nuraini N, Rosandi Y. Nursuprianah I, et al. J Pers Med. 2022 Sep 7;12(9):1469. doi: 10.3390/jpm12091469. J Pers Med. 2022. PMID: 36143254 Free PMC article. Review.
Which Clinical and Biochemical Parameters Are Associated with Lifetime Suicide Attempts in Bipolar Disorder?
Surace T, Capuzzi E, Caldiroli A, Ceresa A, Esposito CM, Auxilia AM, Tagliabue I, Capellazzi M, Legnani F, Di Paolo M, Cirella L, Zanelli Quarantini F, Signorelli MS, Aguglia E, Clerici M, Buoli M. Surace T, et al. Diagnostics (Basel). 2022 Sep 13;12(9):2215. doi: 10.3390/diagnostics12092215. Diagnostics (Basel). 2022. PMID: 36140615 Free PMC article.
A systematic review of the literature on telepsychiatry for bipolar disorder.
Farrell A, George N, Amado S, Wozniak J. Farrell A, et al. Brain Behav. 2022 Oct;12(10):e2743. doi: 10.1002/brb3.2743. Epub 2022 Sep 14. Brain Behav. 2022. PMID: 36102239 Free PMC article. Review.
The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management.
McIntyre RS, Alda M, Baldessarini RJ, Bauer M, Berk M, Correll CU, Fagiolini A, Fountoulakis K, Frye MA, Grunze H, Kessing LV, Miklowitz DJ, Parker G, Post RM, Swann AC, Suppes T, Vieta E, Young A, Maj M. McIntyre RS, et al. World Psychiatry. 2022 Oct;21(3):364-387. doi: 10.1002/wps.20997. World Psychiatry. 2022. PMID: 36073706 Free PMC article.

See all "Cited by" articles

References

1. Rihmer Z., Dome P. Suicide and Bipolar Disorder. In: Zarate C.A.J., Manji H.K., editors. Bipolar Depression: Molecular Neurobiology, Clinical Diagnosis, and Pharmacotherapy. 2nd ed. Springer; Bern, Switzerland: 2017.
1. Rihmer Z., Gonda X., Döme P. The Assessment and Management of SuicideRrisk in Bipolar Disorder. In: Carvalho A.F., Vieta E., editors. The Treatment of Bipolar Disorder: Integrative Clinical Strategies and Future Directions. Oxford University Press; Oxford, UK: 2017.
1. Staudt Hansen P., Frahm Laursen M., Grontved S., Puggard Vogt Straszek S., Licht R.W., Nielsen R.E. Increasing mortality gap for patients diagnosed with bipolar disorder—A nationwide study with 20 years of follow-up. Bipolar Disord. 2019;21:270–275. doi: 10.1111/bdi.12684. - DOI - PubMed
1. Hayes J.F., Marston L., Walters K., King M.B., Osborn D.P.J. Mortality gap for people with bipolar disorder and schizophrenia: UK-based cohort study 2000–2014. Br. J. Psychiatry. 2017;211:175–181. doi: 10.1192/bjp.bp.117.202606. - DOI - PMC - PubMed
1. Bauer M., Andreassen O.A., Geddes J.R., Vedel Kessing L., Lewitzka U., Schulze T.G., Vieta E. Areas of uncertainties and unmet needs in bipolar disorders: Clinical and research perspectives. Lancet Psychiatry. 2018;5:930–939. doi: 10.1016/S2215-0366(18)30253-0. - DOI - PubMed

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions

LinkOut - more resources

Full Text Sources
Medical

[1] Rihmer Z., Dome P. Suicide and Bipolar Disorder. In: Zarate C.A.J., Manji H.K., editors. Bipolar Depression: Molecular Neurobiology, Clinical Diagnosis, and Pharmacotherapy. 2nd ed. Springer; Bern, Switzerland: 2017.

[2] Rihmer Z., Dome P. Suicide and Bipolar Disorder. In: Zarate C.A.J., Manji H.K., editors. Bipolar Depression: Molecular Neurobiology, Clinical Diagnosis, and Pharmacotherapy. 2nd ed. Springer; Bern, Switzerland: 2017.

[3] Rihmer Z., Gonda X., Döme P. The Assessment and Management of SuicideRrisk in Bipolar Disorder. In: Carvalho A.F., Vieta E., editors. The Treatment of Bipolar Disorder: Integrative Clinical Strategies and Future Directions. Oxford University Press; Oxford, UK: 2017.

[4] Rihmer Z., Gonda X., Döme P. The Assessment and Management of SuicideRrisk in Bipolar Disorder. In: Carvalho A.F., Vieta E., editors. The Treatment of Bipolar Disorder: Integrative Clinical Strategies and Future Directions. Oxford University Press; Oxford, UK: 2017.

[5] Staudt Hansen P., Frahm Laursen M., Grontved S., Puggard Vogt Straszek S., Licht R.W., Nielsen R.E. Increasing mortality gap for patients diagnosed with bipolar disorder—A nationwide study with 20 years of follow-up. Bipolar Disord. 2019;21:270–275. doi: 10.1111/bdi.12684. - DOI - PubMed

[6] Staudt Hansen P., Frahm Laursen M., Grontved S., Puggard Vogt Straszek S., Licht R.W., Nielsen R.E. Increasing mortality gap for patients diagnosed with bipolar disorder—A nationwide study with 20 years of follow-up. Bipolar Disord. 2019;21:270–275. doi: 10.1111/bdi.12684. - DOI - PubMed

[7] Hayes J.F., Marston L., Walters K., King M.B., Osborn D.P.J. Mortality gap for people with bipolar disorder and schizophrenia: UK-based cohort study 2000–2014. Br. J. Psychiatry. 2017;211:175–181. doi: 10.1192/bjp.bp.117.202606. - DOI - PMC - PubMed

[8] Hayes J.F., Marston L., Walters K., King M.B., Osborn D.P.J. Mortality gap for people with bipolar disorder and schizophrenia: UK-based cohort study 2000–2014. Br. J. Psychiatry. 2017;211:175–181. doi: 10.1192/bjp.bp.117.202606. - DOI - PMC - PubMed

[9] Bauer M., Andreassen O.A., Geddes J.R., Vedel Kessing L., Lewitzka U., Schulze T.G., Vieta E. Areas of uncertainties and unmet needs in bipolar disorders: Clinical and research perspectives. Lancet Psychiatry. 2018;5:930–939. doi: 10.1016/S2215-0366(18)30253-0. - DOI - PubMed

[10] Bauer M., Andreassen O.A., Geddes J.R., Vedel Kessing L., Lewitzka U., Schulze T.G., Vieta E. Areas of uncertainties and unmet needs in bipolar disorders: Clinical and research perspectives. Lancet Psychiatry. 2018;5:930–939. doi: 10.1016/S2215-0366(18)30253-0. - DOI - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Suicide Risk in Bipolar Disorder: A Brief Review

Affiliations

Suicide Risk in Bipolar Disorder: A Brief Review

Authors

Affiliations

Abstract

Conflict of interest statement

Similar articles

Cited by

References

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Abstract

Conflict of interest statement

Similar articles

Cited by

References

Publication types

MeSH terms

Substances

Related information

LinkOut - more resources

Full Text Sources

Medical