The use of noncultured regenerative epithelial suspension for improving skin color and scars: A report of 8 cases and review of the literature

J Cosmet Dermatol. 2019 Jul 26. doi: 10.1111/jocd.13071. Online ahead of print.


Background: Regenerative Epithelial Suspension can lead to the restoration of wound and repigmentation, which can be gained by ReCell medical device to treat scar and depigmentation diseases.

Objectives: To report the effectivity of ReCell combined with microdermabrasion in scar and depigmentation diseases and review the literature of this new technology.

Methods: We gave a differential donor⁄recipient ratio of about 1:20-30 with vitiligo, 1:40 with postburn construction, 1:80 with acne scar, and 1:120 with adult congenital melanocytic nevus, 1:80 with pediatrics, respectively. Photographs of patients before treatment and 3 months following the last treatment session were used to evaluate the effectivity.

Results: A total of 8 patients including vitiligo vulgaris, postburn reconstruction, acne scars, and congenital melanocytic nevi treated by ReCell technology combined with microdermabrasion showed significant improvement in skin texture and color. And 17 studies of the research on ReCell technology were totally included in the systematic review.

Conclusion: Our investigation showed that Regenerative Epithelial Suspension gained by ReCell technology combined with microdermabrasion may improve scar and depigmentation diseases.

Keywords: acne; burn; noncultured autologous cell; scar; vitiligo.