Liquid and Vapour Phase of Lavandin (Lavandula × intermedia) Essential Oil: Chemical Composition and Antimicrobial Activity

Molecules. 2019 Jul 25;24(15):2701. doi: 10.3390/molecules24152701.


Essential oils from Lavandula genus and the obtained hybrids are widely used for different purposes such as perfume production in the cosmetic field and for its biological properties. This is the first study on the liquid and vapour phase of Lavandula × intermedia "Grosso" essential oil grown in the Lazio Region, Italy, investigated using headspace coupled to gas chromatography and mass spectrometry (HS-GC/MS). The results showed the most abundant components were linalool and linalyl acetate, followed by 1,8-cineole and terpinen-4-ol, while lavandulyl acetate and borneol were identified as minor compounds, maintaining the same proportion in both the liquid and vapour phase. Furthermore, we tested lavandin liquid and vapour phase essential oil on gram-negative bacteria (Escherichia coli, Acinetobacter bohemicus, and Pseudomonas fluorescens) and gram-positive bacteria (Bacillus cereus and Kocuria marina).

Keywords: HS-GC/MS analysis; antibacterial activity; lavandin essential oil; liquid phase; vapour phase.

MeSH terms

  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / pharmacology
  • Gas Chromatography-Mass Spectrometry
  • Lavandula / chemistry*
  • Microbial Sensitivity Tests
  • Oils, Volatile / chemistry*
  • Oils, Volatile / pharmacology*
  • Phase Transition*
  • Phytochemicals / chemistry
  • Phytochemicals / pharmacology
  • Plant Extracts / chemistry*
  • Plant Extracts / pharmacology*


  • Anti-Infective Agents
  • Oils, Volatile
  • Phytochemicals
  • Plant Extracts