Racial disparities, cancer and response to oxidative stress

Abstract

At the intersection of genetics, biochemistry and behavioral sciences, there is a largely untapped opportunity to consider how ethnic and racial disparities contribute to individual sensitivity to reactive oxygen species and how these might influence susceptibility to various cancers and/or response to classical cancer treatment regimens that pervasively result in the formation of such chemical species. This chapter begins to explore these connections and builds a platform from which to consider how the disciplines can be strengthened further.

Keywords: Glutathione; Glutathione S-transferases; Oxidative stress; Polymorphisms; Racial disparities; Redox.