Citrobacter koseri causing osteomyelitis in a diabetic foot with concomitant acute gouty arthritis successfully treated with ertapenem

BMJ Case Rep. 2019 Jul 27;12(7):e230432. doi: 10.1136/bcr-2019-230432.

Abstract

We present an elderly diabetic man with left hallux pain and drainage who was initially diagnosed with acute gouty arthritis using the diagnostic rule for acute gout and monosodium urate crystals presented on synovial fluid analysis. Further investigation with surgical debridement, plain X-ray, MRI and wound culture revealed concomitant Citrobacter koseri septic arthritis with osteomyelitis. C. koseri is considered an opportunistic infection that rarely causes musculoskeletal infections. Acute gouty arthritis and septic arthritis are rarely seen occurring concomitantly in the same joint and are often difficult to differentiate due to similar findings on exam and imaging. The present case illustrates that osteomyelitis with an opportunistic organism can present concomitantly with acute gouty arthritis, and the diagnosis of one should not exclude the other.

Keywords: diabetes; infections; musculoskeletal and joint disorders; pain.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use*
  • Arthritis, Gouty / microbiology*
  • Arthritis, Gouty / therapy
  • Citrobacter koseri / pathogenicity*
  • Debridement
  • Diabetic Foot / microbiology
  • Diabetic Foot / physiopathology*
  • Enterobacteriaceae Infections / diagnosis*
  • Enterobacteriaceae Infections / physiopathology
  • Enterobacteriaceae Infections / therapy
  • Ertapenem / therapeutic use*
  • Humans
  • Male
  • Osteomyelitis / diagnosis*
  • Osteomyelitis / physiopathology
  • Osteomyelitis / therapy
  • Piperacillin, Tazobactam Drug Combination / therapeutic use
  • Treatment Outcome
  • Vancomycin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Piperacillin, Tazobactam Drug Combination
  • Vancomycin
  • Ertapenem