Management of gonococcal ophthalmia neonatorum with single-dose kanamycin and ocular irrigation with saline

Sex Transm Dis. Apr-Jun 1988;15(2):108-9. doi: 10.1097/00007435-198804000-00008.

Abstract

Two hundred nineteen neonates with gonococcal ophthalmia neonatorum, including 40 infected with penicillinase-producing strains, were treated as outpatients with a single intramuscular injection of 100 mg of kanamycin and hourly ocular irrigation with saline. Neisseria gonorrhoeae was isolated from three (1.4%) of the 212 babies attending for follow-up, and post-gonococcal conjunctivitis developed in 22 (10.4%) of those who returned for follow-up.

MeSH terms

  • Ambulatory Care
  • Female
  • Gonorrhea / drug therapy*
  • Gonorrhea / microbiology
  • Humans
  • Infant, Newborn
  • Kanamycin / administration & dosage
  • Kanamycin / therapeutic use*
  • Male
  • Neisseria gonorrhoeae / isolation & purification
  • Ophthalmia Neonatorum / drug therapy*
  • Ophthalmia Neonatorum / microbiology
  • Saline Solution, Hypertonic / administration & dosage*
  • Sodium Chloride / administration & dosage*
  • Therapeutic Irrigation

Substances

  • Saline Solution, Hypertonic
  • Sodium Chloride
  • Kanamycin