Early Operative Versus Nonoperative Treatment of Fragility Fractures of the Pelvis: A Propensity-Matched Multicenter Study

J Orthop Trauma. 2019 Nov;33(11):e410-e415. doi: 10.1097/BOT.0000000000001584.

Abstract

Objective: To compare early operative treatment with nonoperative treatment of fragility fractures of the pelvis regarding mortality and functional outcome.

Design: Retrospective.

Setting: Two trauma centers.

Patients and methods: Two hundred thirty consecutive patients 60 years of age or older with an isolated low-energy fracture of the pelvis and with a follow-up of at least 24 months. In center 1, treatment consisted of a nonoperative attempt and early operative fixation if mobilization was not possible. In center 2, all patients were treated nonoperatively.

Main outcome measurements: Primary outcome was mortality. Secondary outcomes were in-hospital complications. Patients who survived were contacted by phone, and a modified Majeed score was obtained to assess functional outcome at the final follow-up.

Results: At the final follow-up (mean 61 months, SD 24), 105/230 (45.7%) patients had died. One year after the initial hospitalization, 34/148 patients [23%, 95% confidence interval (CI): 17%-31%] of the early operative group and 14/82 patients (17%, 95% CI: 10%-27%) of the nonoperative group had died (P = 0.294). Nonoperative treatment had a protective effect on survival during the first 2 years (hazard ratio of the nonlinear effect: 2.86, 95% CI: 1.38-5.94, P < 0.001). Patients in the early operative treatment group who survived the first 2 years had a better long-term survival. The functional outcome at the end of follow-up as measured by a modified Majeed score was not different between the 2 groups (early operative: 66.1, SD 12.6 vs. nonoperative: 65.7, SD 12.5, P = 0.910).

Conclusion: Early operative fixation of patients who cannot be mobilized within 3-5 days was associated with a higher mortality rate and complication rate at 1 year but with a better long-term survival after more than 2 years. Hence, patients with a life expectancy of less than 2 years may not benefit from surgery with regard to survival.

Level of evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cohort Studies
  • Conservative Treatment / methods*
  • Early Ambulation
  • Female
  • Follow-Up Studies
  • Fracture Fixation, Internal / adverse effects
  • Fracture Fixation, Internal / methods*
  • Fracture Healing / physiology
  • Fractures, Bone / diagnostic imaging
  • Fractures, Bone / mortality
  • Fractures, Bone / surgery*
  • Fractures, Bone / therapy
  • Humans
  • Injury Severity Score
  • Kaplan-Meier Estimate
  • Male
  • Osteoporotic Fractures / diagnostic imaging
  • Osteoporotic Fractures / mortality
  • Osteoporotic Fractures / surgery*
  • Osteoporotic Fractures / therapy
  • Propensity Score
  • Proportional Hazards Models
  • Retrospective Studies
  • Risk Assessment
  • Secondary Prevention
  • Survival Analysis
  • Switzerland
  • Time Factors
  • Trauma Centers
  • Treatment Outcome