Differentiation of Gastric Schwannoma From Gastric Gastrointestinal Stromal Tumor With Dual-Phase Contrast-Enhanced Computed Tomography

J Comput Assist Tomogr. 2019 Sep/Oct;43(5):741-746. doi: 10.1097/RCT.0000000000000902.

Abstract

Objective: To identify the computed tomographic features to differentiate gastric schwannoma from gastric gastrointestinal stromal tumor.

Methods: Computed tomographic images of 103 pathologically confirmed patients with gastric schwannoma (n = 23) or gastric gastrointestinal stromal tumor (n = 80) were retrospectively studied. Sex, morphology, location, border, growth pattern, enhancement pattern, necrosis, calcification, ulceration, and perigastric lymph nodes were analyzed. Age, short diameter, long diameter, and the degree of enhancement were measured. Statistical analyses were performed, and receiver operating characteristic curve, sensitivity, and specificity values were analyzed.

Results: Female, age younger than 57.5 years, round or ovoid morphology, extraluminal growth, homogeneous enhancement, lack of necrosis, presence of perigastric lymph nodes, and an enhancement degree of less than 15.4 Hounsfield units in the arterial phase were significant variables for differentiating gastric schwannoma from gastric gastrointestinal stromal tumor (P < 0.05).

Conclusions: Dual-phase contrast-enhanced computed tomography can help to differentiate gastric schwannoma from gastric gastrointestinal stromal tumor.

MeSH terms

  • Adult
  • Aged
  • Contrast Media / administration & dosage
  • Diagnosis, Differential
  • Female
  • Gastrointestinal Stromal Tumors / diagnostic imaging*
  • Gastrointestinal Stromal Tumors / pathology
  • Humans
  • Iopamidol / administration & dosage
  • Male
  • Middle Aged
  • Neurilemmoma / diagnostic imaging*
  • Neurilemmoma / pathology
  • Retrospective Studies
  • Sensitivity and Specificity
  • Stomach Neoplasms / diagnostic imaging*
  • Stomach Neoplasms / pathology
  • Tomography, X-Ray Computed / methods*

Substances

  • Contrast Media
  • Iopamidol