Refractory α/β-Hepatosplenic T-cell Lymphoma With Secondary CNS Dissemination and Severe Morbidity Related to Intrathecal Chemotherapy: A Case Report and Literature Review

Clin Lymphoma Myeloma Leuk. 2019 Oct;19(10):e564-e567. doi: 10.1016/j.clml.2019.05.014. Epub 2019 May 29.
No abstract available

Keywords: CNS relapse; Chemo-refractory; Hepatosplenic T-cell lymphoma; Intrathecal; Myelopathy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Central Nervous System / drug effects*
  • Central Nervous System / pathology
  • Central Nervous System Diseases / chemically induced
  • Central Nervous System Diseases / diagnostic imaging
  • Drug Resistance, Neoplasm
  • Fatal Outcome
  • Female
  • Humans
  • Injections, Spinal
  • Liver / pathology*
  • Lymphoma, T-Cell / drug therapy*
  • Lymphoma, T-Cell / metabolism
  • Lymphoma, T-Cell / pathology
  • Magnetic Resonance Imaging / methods
  • Positron Emission Tomography Computed Tomography / methods
  • Receptors, Antigen, T-Cell, alpha-beta / metabolism*
  • Spleen / pathology*

Substances

  • Receptors, Antigen, T-Cell, alpha-beta