Aims and objectives: The aim of this study was to compare the in vitro efficacy of different remineralization (RM) agents on RM of artificial caries by evaluating the density, light reflection, and the crystal size of the newly formed mineral in primary and permanent teeth.
Materials and methods: Caries-free primary and permanent molars were divided into seven groups (n = 20) and treated with: G1 - Deionized water, G2 - Colgate Cavity Protection, G3 - Sensodyne Rapid Relief, G4 - GC MI Paste Plus, G5 - Clinpro Tooth Creme, G6 - Clinpro 5000, and G7 - Sensodyne Repair and Protect. Lesion depths were evaluated using laser fluorescence (DIAGNOdent), and polarized light microscopy (PLM), and the minerals were evaluated using X-ray diffractometry (XRD).
Results: The highest decrease in laser fluorescence readings was observed in G6 for both primary and permanent teeth. No significant difference was observed between G2, G4, G5, and G6 in permanent teeth and G4 and G6 in primary teeth (P > 0.05). In PLM analyses, lesions depths were found to be lower in G6 compared to the other groups. No significant difference was observed between G2, G4, and G6 (P < 0.05). XRD evaluation showed that the newly formed mineral in G6 was denser and highly crystallized compared to the other groups.
Conclusion: This in vitro study demonstrated that Clinpro 5000 is more efficient in remineralizing incipient enamel lesions compared to the other agents tested.
Keywords: DIAGNOdent; X-ray diffractometry; initial enamel lesion; polarized light microscopy; remineralization.
Conflict of interest statement
There are no conflicts of interest.
Remineralizing Efficacy of Different Calcium-Phosphate and Fluoride Based Delivery Vehicles on Artificial Caries Like Enamel LesionsD Elkassas et al. J Dent 42 (4), 466-74. PMID 24412586.Remineralizing agents containing different calcium-phosphate formulas and fluoride have increased remineralization potential compared to artificial saliva. Clinpro™ varni …
In Vitro Remineralization of Enamel Subsurface Lesions and Assessment of Dentine Tubule Occlusion From NaF Dentifrices With and Without CalciumAR Prabhakar et al. J Indian Soc Pedod Prev Dent 31 (1), 29-35. PMID 23727740. - Randomized Controlled TrialWithin the limitations of our study, sodium fluoride showed relatively greatest remineralizing and dentinal tubule occlusion property when compared with GC MI paste plus …
Silver Diamine Fluoride Remineralized Artificial Incipient Caries in Permanent Teeth After Bacterial pH-cycling In-VitroK Punyanirun et al. J Dent 69, 55-59. PMID 28918101.The adjunctive use of 38% SDF enhances the remineralization of initial carious lesions based on mineral density, depth, and remineralization percentage compared with the …
Remineralization Efficacy of a Toothpaste Containing 8% Arginine and Calcium Carbonate on Enamel SurfaceY Huang et al. Am J Dent 26 (5), 291-7. PMID 24479283.All test products showed a recovery of the Knoop Hardness Number (KHN) after remineralization cycling treatment. The recovery of enamel KHN for Colgate Sensitive Pro-Reli …
In Vitro Assessment of 3 Dentifrices Containing Fluoride in Preventing Demineralization of Overdenture Abutments and Root SurfacesZS Goettsche et al. J Prosthet Dent 112 (5), 1257-64. PMID 25277038.The addition of tricalcium phosphate or calcium phosphosilicate to fluoride-containing dentifrices (5000 ppm) does not significantly improve their ability to prevent demi …
- Featherstone JD. Prevention and reversal of dental caries: Role of low-level fluoride. Community Dent Oral Epidemiol. 1999;27:31–40. - PubMed
- Mir NA, Higuchi WI, Hefferren JJ. The mechanism of action of solution fluoride upon the demineralization rate of human enamel. Arch Oral Biol. 1969;14:901–20. - PubMed
- Reynolds EC. Anticariogenic complexes of amorphous calcium phosphate stabilized by casein phosphopeptides: A review. Spec Care Dentist. 1998;18:8–16. - PubMed
- Ardu S, Castioni NV, Benbachir N, Krejci I. Minimally invasive treatment of white spot enamel lesions. Quintessence Int. 2007;38:633–6. - PubMed
- Walsh LJ. Contemporary technologies for remineralization therapies: A review. Int Dent SA. 2009;11:6–16.