A new triterpenoid and other compounds from lichens Cryptothecia faveomaculata Makhija & Patw

Nat Prod Res. 2021 Apr;35(8):1349-1356. doi: 10.1080/14786419.2019.1648466. Epub 2019 Aug 2.

Abstract

Ten compounds (1-10) were purified from the extract of lichens C. faveomaculata, and among these one new triterpenoid, cryptothecin A (1) was characterized through mass spectrometric and 2D NMR spectroscopic analyses. Some of the isolated compounds were assessed for their antimicrobial (1, 6, and 8) and cytotoxic activity (1, 4-5, and 7-9), but only weak inhibitory effects were observed.

Keywords: Lichen; antibacterial; steroid; triterpenoid.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Anti-Infective Agents / isolation & purification
  • Antineoplastic Agents / pharmacology
  • Bacteria / drug effects
  • Carbon-13 Magnetic Resonance Spectroscopy
  • Cell Line, Tumor
  • Fungi / drug effects
  • Humans
  • Lichens / chemistry*
  • Microbial Sensitivity Tests
  • Proton Magnetic Resonance Spectroscopy
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antineoplastic Agents
  • Triterpenes