Stable Ischemic Heart Disease

Ann Intern Med. 2019 Aug 6;171(3):ITC17-ITC32. doi: 10.7326/AITC201908060.


Stable ischemic heart disease (SIHD) is a leading cause of death in the United States and many other countries. The defining pathobiology is an imbalance between the metabolic demands of the myocardium and its oxygen supply, which most often results from coronary artery atherosclerosis. The classic presenting symptom of SIHD is angina, but clinical presentation varies greatly among patients. Since the last In the Clinic on SIHD in 2014, several new drugs have been approved to reduce ischemic complications, such as myocardial infarction and congestive heart failure.

Publication types

  • Review

MeSH terms

  • Cardiovascular Agents / therapeutic use
  • Coronary Artery Bypass
  • Diagnosis, Differential
  • Heart Failure / prevention & control
  • Humans
  • Myocardial Infarction / prevention & control
  • Myocardial Ischemia* / diagnosis
  • Myocardial Ischemia* / drug therapy
  • Myocardial Ischemia* / physiopathology
  • Myocardial Ischemia* / surgery
  • Patient Education as Topic
  • Risk Factors
  • Risk Reduction Behavior


  • Cardiovascular Agents