Aspirin killed the cat: animal research models do not always apply to humans

Expert Opin Drug Metab Toxicol. 2019 Sep;15(9):683-685. doi: 10.1080/17425255.2019.1652596. Epub 2019 Aug 5.
No abstract available

Keywords: Activity-based protein profiling; animal-free; bioassay; genomics; metabolomics; patient safety; proteomics; three Rs.

Publication types

  • Editorial

MeSH terms

  • Animals
  • Aspirin / administration & dosage
  • Aspirin / metabolism
  • Aspirin / toxicity*
  • Cats
  • Drug Development / methods*
  • Drug Evaluation, Preclinical / methods
  • Humans
  • Models, Animal*
  • Species Specificity
  • Toxicity Tests / methods*

Substances

  • Aspirin