Comparing effects of aromatherapy with lavender essential oil and orange essential oil on fatigue of hemodialysis patients: A randomized trial

Complement Ther Clin Pract. 2019 Aug;36:64-68. doi: 10.1016/j.ctcp.2019.05.005. Epub 2019 May 29.


Background and purpose: Fatigue is a common complication of hemodialysis. This study aimed to compare the effects of aromatherapy with essential oils of lavender and orange on the fatigue of hemodialysis patients.

Materials and methods: Ninety subjects were randomly allocated into three groups of aromatherapy with lavender essential oil, aromatherapy with orange essential oil and control. Data collection tool was the Fatigue Severity Scale. In each experimental group, subjects inhaled five drops of lavender essential oil and orange essential oil.

Results: The difference in the mean of fatigue before and after the intervention in each of the experimental groups was statistically significant, but this difference was not significant in the control group. Between the two groups of aromatherapy, no significant difference was observed in terms of the mean fatigue after the intervention.

Conclusion: Aromatherapy with lavender essential oil and orange essential oil might reduce fatigue in hemodialysis patients.

Keywords: Aromatherapy; Fatigue; Hemodialysis; Lavender essential oil; Orange essential oil.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aromatherapy*
  • Fatigue* / etiology
  • Fatigue* / therapy
  • Humans
  • Oils, Volatile / therapeutic use*
  • Plant Oils / therapeutic use*
  • Renal Dialysis / adverse effects*


  • Oils, Volatile
  • Plant Oils
  • orange oil
  • lavender oil