Genetics: Segregation of Mitochondrial Genomes in the Germline

Curr Biol. 2019 Aug 5;29(15):R746-R748. doi: 10.1016/j.cub.2019.06.029.

Abstract

Mitochondrial genomes are present in hundreds of copies per cell. Recent work now reports the levels of inheritance of mtDNA heteroplasmy in humans and also explores mechanisms that restrict the inheritance of deleterious mtDNA variants in the Drosophila female germline.

Publication types

  • Comment

MeSH terms

  • Animals
  • DNA, Mitochondrial*
  • Drosophila / genetics
  • Female
  • Genome, Mitochondrial*
  • Germ Cells
  • Humans
  • Mitochondria / genetics

Substances

  • DNA, Mitochondrial