Effect of palmitate, acetate and glucose on glutamine metabolism in Ehrlich ascites tumor cells

Biochimie. 1988 Jun;70(6):833-4. doi: 10.1016/0300-9084(88)90114-9.

Abstract

Acetate and the long chain free fatty acid palmitate provoked a decrease in the rates of glutamine utilization and glutamate production in Ehrlich ascites tumor cells incubated with 0.5 mM glutamine. There was a cumulative effect with glucose on glutamine metabolism.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetates / pharmacology*
  • Animals
  • Carcinoma, Ehrlich Tumor / metabolism*
  • Glucose / pharmacology*
  • Glutamates / metabolism*
  • Palmitates / pharmacology*
  • Palmitic Acids / pharmacology*
  • Tumor Cells, Cultured / drug effects
  • Tumor Cells, Cultured / metabolism

Substances

  • Acetates
  • Glutamates
  • Palmitates
  • Palmitic Acids
  • Glucose