Linear IgA Disease: A Rare Complication of Vancomycin

Cureus. 2019 Jun 6;11(6):e4848. doi: 10.7759/cureus.4848.


Linear immunoglobulin A (IgA) bullous dermatosis, also known as linear IgA disease, is a rare disorder with an incidence of about 0.5 to 2.3 cases per million individuals per year. In most of the cases, the cause is unknown; however, 50% of the cases are drug-induced. The disease has bimodal age predilection and occurs in children up to the age of 10 years and in adults usually after the age of 60 years. Common drugs that have been known to cause this disease include vancomycin, lithium, amiodarone, captopril, and some of the nonsteroidal anti-inflammatory agents. We report a case of linear IgA disease secondary to vancomycin.

Keywords: linear iga disease; vancomycin.

Publication types

  • Case Reports