Diagnosis and management of sepsis-induced coagulopathy and disseminated intravascular coagulation

doi:10.1111/jth.14578

Review

. 2019 Nov;17(11):1989-1994.

doi: 10.1111/jth.14578. Epub 2019 Aug 13.

Diagnosis and management of sepsis-induced coagulopathy and disseminated intravascular coagulation

Toshiaki Iba¹, Jerrold H Levy², Theodore E Warkentin³, Jecko Thachil⁴, Tom van der Poll⁵, Marcel Levi⁶; Scientific and Standardization Committee on DIC, and the Scientific and Standardization Committee on Perioperative and Critical Care of the International Society on Thrombosis and Haemostasis

Affiliations

¹ Department of Emergency and Disaster Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
² Department of Anesthesiology, Critical Care, and Surgery, Duke University School of Medicine, Durham, NC, USA.
³ Department of Pathology and Molecular Medicine, and Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
⁴ Department of Haematology, Manchester Royal Infirmary, Manchester, UK.
⁵ Amsterdam University Medical Centers, Location Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
⁶ University College London Hospitals NHS Foundation Trust, London, UK.

PMID: 31410983
DOI: 10.1111/jth.14578

Free article

Review

Diagnosis and management of sepsis-induced coagulopathy and disseminated intravascular coagulation

Toshiaki Iba et al. J Thromb Haemost. 2019 Nov.

Free article

. 2019 Nov;17(11):1989-1994.

doi: 10.1111/jth.14578. Epub 2019 Aug 13.

Authors

Affiliations

¹ Department of Emergency and Disaster Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
² Department of Anesthesiology, Critical Care, and Surgery, Duke University School of Medicine, Durham, NC, USA.
³ Department of Pathology and Molecular Medicine, and Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
⁴ Department of Haematology, Manchester Royal Infirmary, Manchester, UK.
⁵ Amsterdam University Medical Centers, Location Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
⁶ University College London Hospitals NHS Foundation Trust, London, UK.

PMID: 31410983
DOI: 10.1111/jth.14578

No abstract available

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Comment in

The prothrombin time ratio is not a more effective marker for evaluating sepsis-induced coagulopathy than fibrin-related markers.
Wada H, Shiraki K, Shimaoka M. Wada H, et al. J Thromb Haemost. 2020 Jun;18(6):1506-1507. doi: 10.1111/jth.14766. J Thromb Haemost. 2020. PMID: 32496020 No abstract available.
RE: The prothrombin time ratio is not a more effective marker for evaluating sepsis-induced coagulopathy than fibrin-related markers: Response to the Letter-to-the-Editor by Dr Wada.
Iba T, Levy JH, Warkentin TE, Thachil J, van der Poll T, Levi M. Iba T, et al. J Thromb Haemost. 2020 Jun;18(6):1507-1509. doi: 10.1111/jth.14799. J Thromb Haemost. 2020. PMID: 32496021 No abstract available.

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Cell-free DNA predicts all-cause mortality of sepsis-induced acute kidney injury.
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References

REFERENCES

1. Taylor FB, Toh CH, Hoots WK, WadaHLeviM et al. Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation. Thromb Haemost. 2001;86:1327-30.
1. van der Poll T, van de Veerdonk FL, Scicluna BP, Netea MG. The immunopathology of sepsis and potential therapeutic targets. Nat Rev Immunol. 2017;17:407-20.
1. Iba T, Levy JH. Inflammation and thrombosis: roles of neutrophils, platelets and endothelial cells and their interactions in thrombus formation during sepsis. J Thromb Haemost. 2018;16:231-41.
1. Gando S, Levi M, Toh CH. Disseminated intravascular coagulation. Nat Rev Dis Primers. 2016;2:16037.
1. Umemura Y, Yamakawa K, Ogura H, Yuhara H, Fujimi S. Efficacy and safety of anticoagulant therapy in three specific populations with sepsis: a meta-analysis of randomized controlled trials. J Thromb Haemost. 2016;14:518-30.

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[1] Taylor FB, Toh CH, Hoots WK, WadaHLeviM et al. Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation. Thromb Haemost. 2001;86:1327-30.

[2] Taylor FB, Toh CH, Hoots WK, WadaHLeviM et al. Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation. Thromb Haemost. 2001;86:1327-30.

[3] van der Poll T, van de Veerdonk FL, Scicluna BP, Netea MG. The immunopathology of sepsis and potential therapeutic targets. Nat Rev Immunol. 2017;17:407-20.

[4] van der Poll T, van de Veerdonk FL, Scicluna BP, Netea MG. The immunopathology of sepsis and potential therapeutic targets. Nat Rev Immunol. 2017;17:407-20.

[5] Iba T, Levy JH. Inflammation and thrombosis: roles of neutrophils, platelets and endothelial cells and their interactions in thrombus formation during sepsis. J Thromb Haemost. 2018;16:231-41.

[6] Iba T, Levy JH. Inflammation and thrombosis: roles of neutrophils, platelets and endothelial cells and their interactions in thrombus formation during sepsis. J Thromb Haemost. 2018;16:231-41.

[7] Gando S, Levi M, Toh CH. Disseminated intravascular coagulation. Nat Rev Dis Primers. 2016;2:16037.

[8] Gando S, Levi M, Toh CH. Disseminated intravascular coagulation. Nat Rev Dis Primers. 2016;2:16037.

[9] Umemura Y, Yamakawa K, Ogura H, Yuhara H, Fujimi S. Efficacy and safety of anticoagulant therapy in three specific populations with sepsis: a meta-analysis of randomized controlled trials. J Thromb Haemost. 2016;14:518-30.

[10] Umemura Y, Yamakawa K, Ogura H, Yuhara H, Fujimi S. Efficacy and safety of anticoagulant therapy in three specific populations with sepsis: a meta-analysis of randomized controlled trials. J Thromb Haemost. 2016;14:518-30.

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Diagnosis and management of sepsis-induced coagulopathy and disseminated intravascular coagulation

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Diagnosis and management of sepsis-induced coagulopathy and disseminated intravascular coagulation

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