Cyclic AMP links glucose stimulation to somatostatin secretion in δ-cells

J Gen Physiol. 2019 Sep 2;151(9):1062-1065. doi: 10.1085/jgp.201912417. Epub 2019 Aug 14.

Abstract

Tengholm reflects on new work providing insight into the mechanisms of glucose-stimulated somatostatin secretion from δ-cells.

MeSH terms

  • Animals
  • Cyclic AMP / metabolism*
  • Glucose / metabolism
  • Glucose / pharmacology*
  • Somatostatin / metabolism*
  • Somatostatin-Secreting Cells / drug effects*
  • Somatostatin-Secreting Cells / metabolism*

Substances

  • Somatostatin
  • Cyclic AMP
  • Glucose