Identification of the novel HLA-C*05:01:49 allele in a Brazilian candidate donor for bone marrow donation

HLA. 2019 Nov;94(5):454-455. doi: 10.1111/tan.13666. Epub 2019 Aug 25.

Abstract

Identification of the novel HLA-C*05:01:49 allele that differs from HLA-C*05:01:01:02 in exon 4.

Keywords: Brazil; HLA; HLA-C; Rio de Janeiro; new allele; next-generation sequencing.

MeSH terms

  • Bone Marrow / immunology*
  • Bone Marrow Transplantation / methods*
  • Brazil
  • Exons / genetics
  • HLA-C Antigens / genetics*
  • HLA-C Antigens / immunology*
  • High-Throughput Nucleotide Sequencing
  • Histocompatibility Testing / methods*
  • Humans
  • Polymorphism, Single Nucleotide*
  • Tissue Donors*

Substances

  • HLA-C Antigens
  • HLA-C*05 antigen