Inclusion of key populations in clinical trials of new antituberculosis treatments: Current barriers and recommendations for pregnant and lactating women, children, and HIV-infected persons
PLoS Med. 2019 Aug 15;16(8):e1002882.
doi: 10.1371/journal.pmed.1002882.
eCollection 2019 Aug.
1 Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
2 Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, United States of America.
3 Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.
Amita Gupta and colleagues discuss priorities in clinical research aimed at improving tuberculosis prevention and treatment in pregnant women, children, and people with HIV.
Publication types
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
MeSH terms
Antitubercular Agents / therapeutic use*
Child
Clinical Trials as Topic / methods*
Coinfection / microbiology
Coinfection / virology
Female
HIV Infections / complications*
Humans
Lactation
Patient Selection*
Pregnancy
Pregnancy Complications, Infectious / drug therapy*