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Review
. 2020 Jan;63(1):3-9.
doi: 10.1007/s00125-019-04977-9. Epub 2019 Aug 16.

Cognitive Dysfunction in Diabetes: How to Implement Emerging Guidelines

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Free PMC article
Review

Cognitive Dysfunction in Diabetes: How to Implement Emerging Guidelines

Geert J Biessels et al. Diabetologia. .
Free PMC article

Abstract

Cognitive dysfunction, including mild cognitive impairment and dementia, is increasingly recognised as an important comorbidity and complication of diabetes that affects an individual's well-being and diabetes management, and is associated with diabetes treatment-related complications. Recent guidelines therefore recommend screening for cognitive impairment in older individuals with diabetes. In addition, these guidelines suggest that glucose-lowering treatment should be tailored in those diagnosed with cognitive impairment, to reduce the risk of hypoglycaemia and improve treatment adherence. This review gives an overview of cognitive dysfunction in people with diabetes, briefly describing the clinical features of different stages of cognitive dysfunction and their epidemiology. In particular, it addresses essential additional steps that need to be taken to fully implement the emerging guidelines on screening and management of cognitive dysfunction in diabetes into daily practice.

Keywords: Alzheimer’s disease; Cognitive dysfunction; Dementia; Guidelines; Implementation; Mild cognitive impairment; Review; Screening; Type 1 diabetes; Type 2 diabetes.

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References

    1. Biessels GJ, Despa F. Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications. Nat Rev Endocrinol. 2018;14(10):591–604. doi: 10.1038/s41574-018-0048-7. - DOI - PMC - PubMed
    1. International Diabetes Federation (IDF) (2017) IDF diabetes atlas, 8th ed, 2017. Available from www.diabetesatlas.org/resources/2017-atlas.html. Accessed 15 March 2019
    1. Alzheimer’s Disease International (2015) World Alzheimer report 2015: the global impact of dementia. Available from https://www.alz.co.uk/research/world-report-2015. Accessed 15 March 2019
    1. Feil DG, Rajan M, Soroka O, Tseng CL, Miller DR, Pogach LM. Risk of hypoglycemia in older veterans with dementia and cognitive impairment: implications for practice and policy. J Am Geriatr Soc. 2011;59(12):2263–2272. doi: 10.1111/j.1532-5415.2011.03726.x. - DOI - PubMed
    1. Dolan C, Glynn R, Griffin S, et al. Brain complications of diabetes mellitus: a cross-sectional study of awareness among individuals with diabetes and the general population in Ireland. Diabet Med. 2018;35(7):871–879. doi: 10.1111/dme.13639. - DOI - PubMed

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