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. 2020 Jan;63(1):3-9.
doi: 10.1007/s00125-019-04977-9. Epub 2019 Aug 16.

Cognitive Dysfunction in Diabetes: How to Implement Emerging Guidelines

Free PMC article

Cognitive Dysfunction in Diabetes: How to Implement Emerging Guidelines

Geert J Biessels et al. Diabetologia. .
Free PMC article


Cognitive dysfunction, including mild cognitive impairment and dementia, is increasingly recognised as an important comorbidity and complication of diabetes that affects an individual's well-being and diabetes management, and is associated with diabetes treatment-related complications. Recent guidelines therefore recommend screening for cognitive impairment in older individuals with diabetes. In addition, these guidelines suggest that glucose-lowering treatment should be tailored in those diagnosed with cognitive impairment, to reduce the risk of hypoglycaemia and improve treatment adherence. This review gives an overview of cognitive dysfunction in people with diabetes, briefly describing the clinical features of different stages of cognitive dysfunction and their epidemiology. In particular, it addresses essential additional steps that need to be taken to fully implement the emerging guidelines on screening and management of cognitive dysfunction in diabetes into daily practice.

Keywords: Alzheimer’s disease; Cognitive dysfunction; Dementia; Guidelines; Implementation; Mild cognitive impairment; Review; Screening; Type 1 diabetes; Type 2 diabetes.

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    1. Biessels GJ, Despa F. Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications. Nat Rev Endocrinol. 2018;14(10):591–604. doi: 10.1038/s41574-018-0048-7. - DOI - PMC - PubMed
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