Optimal designs for frequentist model averaging
- PMID: 31427825
- PMCID: PMC6690170
- DOI: 10.1093/biomet/asz036
Optimal designs for frequentist model averaging
Abstract
We consider the problem of designing experiments for estimating a target parameter in regression analysis when there is uncertainty about the parametric form of the regression function. A new optimality criterion is proposed that chooses the experimental design to minimize the asymptotic mean squared error of the frequentist model averaging estimate. Necessary conditions for the optimal solution of a locally and Bayesian optimal design problem are established. The results are illustrated in several examples, and it is demonstrated that Bayesian optimal designs can yield a reduction of the mean squared error of the model averaging estimator by up to 45%.
Keywords: Bayesian optimal design; Local misspecification; Model averaging; Model selection; Model uncertainty; Optimal design.
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