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. 2019 Sep;106(3):665-682.
doi: 10.1093/biomet/asz036. Epub 2019 Jul 13.

Optimal designs for frequentist model averaging

Affiliations

Optimal designs for frequentist model averaging

K Alhorn et al. Biometrika. 2019 Sep.

Abstract

We consider the problem of designing experiments for estimating a target parameter in regression analysis when there is uncertainty about the parametric form of the regression function. A new optimality criterion is proposed that chooses the experimental design to minimize the asymptotic mean squared error of the frequentist model averaging estimate. Necessary conditions for the optimal solution of a locally and Bayesian optimal design problem are established. The results are illustrated in several examples, and it is demonstrated that Bayesian optimal designs can yield a reduction of the mean squared error of the model averaging estimator by up to 45%.

Keywords: Bayesian optimal design; Local misspecification; Model averaging; Model selection; Model uncertainty; Optimal design.

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Figures

Fig. 1.
Fig. 1.
The function formula image in (25) evaluated for (a) the design formula image in (28) and (b) the design formula image in (32).

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