An Fe-N co-doped tube-in-tube carbon nanostructure is synthesized for an efficient oxygen reduction reaction. Thanks to its hollow nature, the mesoporous structure is enriched while defects are not prominent, allowing excellent activity (E 1/2 = 0.851 V) and durability together with methanol tolerance in an electrochemistry test under alkaline conditions. Furthermore, when the material is used as the cathode catalyst of a Zn-air battery, the battery exhibits a peak power density of 181.5 mW cm-2.