Management of parathyroid adenoma: An institutional review

J Pak Med Assoc. 2019 Aug;69(8):1205-1208.

Abstract

To assess indications, role of preoperative localization, intra-operative details and post operative recovery of patients who underwent parathyroidectomy. Data of adult patients diagnosed with parathyroid adenoma with primary hyperparathyroidism from January 2006 to September 2016 was retrieved from medical records. Demographics, preoperative investigations, operative details and follow up were studied. Seventeen patients diagnosed with primary hyperparathyroidism (PHPT) due to parathyroid adenoma, were managed by parathyroidectomy by skin collar incision. Median age was 46 (IQR 35 - 57). Median duration of surgery was 80min (IQR of 15-120 min) and median blood loss was 15ml. Thyroid nodules were observed in three patients, which were managed by thyroid lobectomy. Preoperative Sestamibi scan localized adenoma in 14 patients (frequency 82%). Intraoperative methylene blue and endoscopic ultrasound were not used. Parathormone (PTH) and calcium level were decreased in all post operative patients except one and no recurrence was seen on follow up. Parathyroid adenomas can be successfully localized with a pre-operative Sestamibi scan. Surgery remains the mainstay of treatment.

Keywords: Parathyroid adenoma, MIBI scan..

MeSH terms

  • Adenoma / blood
  • Adenoma / diagnostic imaging
  • Adenoma / surgery*
  • Adult
  • Calcium / blood
  • Female
  • Humans
  • Hyperparathyroidism, Primary / blood
  • Hyperparathyroidism, Primary / diagnostic imaging
  • Hyperparathyroidism, Primary / surgery*
  • Iodine Radioisotopes
  • Length of Stay
  • Male
  • Middle Aged
  • Parathyroid Hormone / blood
  • Parathyroid Neoplasms / blood
  • Parathyroid Neoplasms / diagnostic imaging
  • Parathyroid Neoplasms / surgery*
  • Parathyroidectomy / methods*
  • Postoperative Complications / epidemiology
  • Radionuclide Imaging
  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi
  • Tomography, Emission-Computed, Single-Photon
  • Treatment Outcome
  • Ultrasonography, Doppler, Color

Substances

  • Iodine Radioisotopes
  • Parathyroid Hormone
  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi
  • Calcium