ModelTest-NG: A New and Scalable Tool for the Selection of DNA and Protein Evolutionary Models

Mol Biol Evol. 2020 Jan 1;37(1):291-294. doi: 10.1093/molbev/msz189.


ModelTest-NG is a reimplementation from scratch of jModelTest and ProtTest, two popular tools for selecting the best-fit nucleotide and amino acid substitution models, respectively. ModelTest-NG is one to two orders of magnitude faster than jModelTest and ProtTest but equally accurate and introduces several new features, such as ascertainment bias correction, mixture, and free-rate models, or the automatic processing of single partitions. ModelTest-NG is available under a GNU GPL3 license at , last accessed September 2, 2019.

Keywords: efficient algorithms; high-performance computing; phylogenetic inference; phylogenetic model selection.

Publication types

  • Evaluation Study

MeSH terms

  • Amino Acid Substitution*
  • Evolution, Molecular*
  • Genetic Techniques*
  • Models, Genetic*
  • Software