Extraction, Structural Characterization, and Biological Functions of Lycium Barbarum Polysaccharides: A Review

Biomolecules. 2019 Aug 21;9(9):389. doi: 10.3390/biom9090389.

Abstract

Lycium barbarum polysaccharides (LBPs), as bioactive compounds extracted from L. barbarum L. fruit, have been widely explored for their potential health properties. The extraction and structural characterization methods of LBPs were reviewed to accurately understand the extraction method and structural and biological functions of LBPs. An overview of the biological functions of LBPs, such as antioxidant function, antitumor activity, neuroprotective effects, immune regulating function, and other functions, were summarized. This review provides an overview of LBPs and a theoretical basis for further studying and extending the applications of LBPs in the fields of medicine and food.

Keywords: Lycium barbarum polysaccharides; antioxidant activity; antitumor activity; immune regulation; structural characterization.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology
  • Antioxidants / chemistry
  • Antioxidants / metabolism
  • Cell Survival / drug effects
  • Drugs, Chinese Herbal / chemistry*
  • Drugs, Chinese Herbal / metabolism
  • Drugs, Chinese Herbal / pharmacology
  • Fruit / metabolism
  • Gene Expression Regulation / drug effects
  • Humans
  • Lycium / metabolism*
  • Neuroprotective Agents / chemistry
  • Neuroprotective Agents / pharmacology

Substances

  • Antineoplastic Agents
  • Antioxidants
  • Drugs, Chinese Herbal
  • Neuroprotective Agents
  • lycium barbarum polysaccharide