Efficacy of Nutritional Interventions as Stand-Alone or Synergistic Treatments with Exercise for the Management of Sarcopenia

Nutrients. 2019 Aug 23;11(9):1991. doi: 10.3390/nu11091991.

Abstract

Sarcopenia is an age-related and accelerated process characterized by a progressive loss of muscle mass and strength/function. It is a multifactorial process associated with several adverse outcomes including falls, frailty, functional decline, hospitalization, and mortality. Hence, sarcopenia represents a major public health problem and has become the focus of intense research. Unfortunately, no pharmacological treatments are yet available to prevent or treat this age-related condition. At present, the only strategies for the management of sarcopenia are mainly based on nutritional and physical exercise interventions. The purpose of this review is, thus, to provide an overview on the role of proteins and other key nutrients, alone or in combination with physical exercise, on muscle parameters.

Keywords: nutrition; older people; physical exercise; sarcopenia; synergism.

Publication types

  • Review

MeSH terms

  • Age Factors
  • Aged
  • Combined Modality Therapy
  • Exercise Therapy*
  • Humans
  • Middle Aged
  • Muscle Strength*
  • Muscle, Skeletal / pathology
  • Muscle, Skeletal / physiopathology*
  • Nutritional Status
  • Nutritional Support*
  • Nutritive Value
  • Recovery of Function
  • Sarcopenia / diagnosis
  • Sarcopenia / physiopathology
  • Sarcopenia / therapy*
  • Treatment Outcome