We reported a patient with refractory bullous pemphigoid (BP), who had a higher level of eosinophils and serum IgE. The case showed less response to various therapies. Edematous erythema and new blisters appeared constantly. Considering IFN-α-2b treatment could significantly decrease blood eosinophils, we therefore expected that IFN-α-2b could be effective in the treatment of BP. After treated with IFN-α-2b, the patient's good response to the treatment suggested our hypothesis.
Keywords: IFN-α-2b; bullous pemphigoid; refractory.
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