Method for the determination of functional (clottable) fibrinogen by the new family of ACL coagulometers

Thromb Res. 1988 Dec 1;52(5):453-68. doi: 10.1016/0049-3848(88)90029-1.


A new family of coagulometers ACL 100, 200 and 300 (Instrumentation Laboratory, IL) has recently been introduced, in addition to the existing ACL 810. This paper presents a technique to determine clottable fibrinogen using the ACL method based on the measurement of the light scattered from the reaction mixture during a PT test. This technique was found to compare well with the present most commonly used methods.

Publication types

  • Comparative Study

MeSH terms

  • Afibrinogenemia / blood
  • Blood Chemical Analysis / instrumentation*
  • Blood Chemical Analysis / methods
  • Blood Coagulation Tests / instrumentation*
  • Blood Coagulation Tests / methods
  • Evaluation Studies as Topic
  • Fibrin Fibrinogen Degradation Products / analysis
  • Fibrinogen / analysis*
  • Heparin / blood
  • Humans
  • Immunodiffusion
  • Prothrombin Time


  • Fibrin Fibrinogen Degradation Products
  • Fibrinogen
  • Heparin