Assessment of norfloxacin degradation induced by plasma-produced ozone using surface-enhanced Raman spectroscopy

Qing Huang; Cao Fang; Muhammad Muhammad; Guohua Yao

doi:10.1016/j.chemosphere.2019.124618

Assessment of norfloxacin degradation induced by plasma-produced ozone using surface-enhanced Raman spectroscopy

Chemosphere. 2020 Jan:238:124618. doi: 10.1016/j.chemosphere.2019.124618. Epub 2019 Aug 19.

Authors

Qing Huang¹, Cao Fang², Muhammad Muhammad³, Guohua Yao⁴

Affiliations

¹ Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Institute of Technical Biology and Agriculture Engineering, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China; University of Science & Technology of China, Hefei, 230026, China. Electronic address: huangq@ipp.ac.cn.
² Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Institute of Technical Biology and Agriculture Engineering, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China; Anhui Jianzhu University, Hefei, 230601, China.
³ Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Institute of Technical Biology and Agriculture Engineering, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China; University of Science & Technology of China, Hefei, 230026, China.
⁴ Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Institute of Technical Biology and Agriculture Engineering, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.

PMID: 31470309
DOI: 10.1016/j.chemosphere.2019.124618

Abstract

In this work, we employed surface-enhanced Raman spectroscopy (SERS) combined with density functional theory (DFT) calculation to investigate the pathways/mechanisms of the norfloxacin degradation by oxygen plasma produced ozone. The main degradation products were analyzed by the spectroscopic method, which revealed the breakage of the C-F bond and fracture of piperazinyl and quinolone moieties. In particular, we showed that the main degradation pathway was defluorination of norfloxacin, and this process could be quantitatively assessed by our proposed SERS approach.

Keywords: Degradation; Density function theory (DFT); Low-temperature plasma; Norfloxacin; Ozone; Surface-enhanced Raman spectroscopy (SERS).

MeSH terms

Norfloxacin / analysis*
Norfloxacin / chemistry*
Ozone / chemistry*
Plasma Gases / chemistry*
Spectrum Analysis, Raman / methods*
Water Pollutants, Chemical / analysis*
Water Pollutants, Chemical / chemistry*

Substances

Plasma Gases
Water Pollutants, Chemical
Ozone
Norfloxacin