Fatal Acute Motor Axonal Neuropathy Induced by Nivolumab: A Case Report and Literature Review

Clin Genitourin Cancer. 2019 Dec;17(6):e1104-e1107. doi: 10.1016/j.clgc.2019.07.020. Epub 2019 Aug 5.

Authors

Nilgun Yildirim¹, Murat Gonen², Ferhat Balgetir², Muhammed Burak Er²

Affiliations

¹ Department of Medical Oncology, Firat University School of Medicine, Elazıg, Turkey. Electronic address: drnilgunsari@yahoo.com.
² Department of Neurology, Firat University School of Medicine, Elazıg, Turkey.

PMID: 31471269
DOI: 10.1016/j.clgc.2019.07.020

No abstract available

Keywords: Immune-related adverse events; Immunotherapy; Polyneuropathy; Renal cell cancer; Treatment.

Publication types

Case Reports
Review

MeSH terms

Aged
Antineoplastic Agents, Immunological / administration & dosage
Antineoplastic Agents, Immunological / adverse effects*
Axons / drug effects*
Axons / immunology
Carcinoma, Renal Cell / diagnosis
Carcinoma, Renal Cell / drug therapy
Carcinoma, Renal Cell / immunology
Carcinoma, Renal Cell / secondary
Drug Substitution / adverse effects
Fatal Outcome
Humans
Indazoles
Kidney Neoplasms / diagnosis
Kidney Neoplasms / drug therapy
Kidney Neoplasms / immunology
Kidney Neoplasms / pathology
Lymphatic Metastasis / therapy
Male
Motor Neurons / drug effects
Motor Neurons / immunology
Nivolumab / administration & dosage
Nivolumab / adverse effects*
Paraparesis / chemically induced
Paraparesis / immunology*
Polyneuropathies / chemically induced
Polyneuropathies / immunology*
Pyrimidines / administration & dosage
Skin Neoplasms / diagnosis
Skin Neoplasms / drug therapy
Skin Neoplasms / immunology
Skin Neoplasms / secondary
Sulfonamides / administration & dosage

Substances

Antineoplastic Agents, Immunological
Indazoles
Pyrimidines
Sulfonamides
Nivolumab
pazopanib