Role of Radioembolization for Biliary Tract and Primary Liver Cancer

Amy C Taylor; Dilip Maddirela; Sarah B White

doi:10.1016/j.soc.2019.07.001

Role of Radioembolization for Biliary Tract and Primary Liver Cancer

Surg Oncol Clin N Am. 2019 Oct;28(4):731-743. doi: 10.1016/j.soc.2019.07.001.

Authors

Amy C Taylor¹, Dilip Maddirela², Sarah B White³

Affiliations

¹ Radiology Consultants of Little Rock, 9601 Baptist Health Drive, Suite 1100, Little Rock, AR 72205, USA.
² Department of Radiology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
³ Department of Radiology, Division of Vascular and Interventional Radiology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA. Electronic address: sbwhite@mcw.edu.

PMID: 31472916
DOI: 10.1016/j.soc.2019.07.001

Abstract

Hepatocellular carcinoma and intrahepatic cholangiocarcinoma are often amenable to locoregional therapy, including percutaneous ablation, transarterial chemoembolization (TACE), or transarterial radioembolization (TARE). TARE is a technique that delivers a high dose of radiation to the tumor, while limiting the dose to the normal liver parenchyma and the adjacent organs. It has been shown to effectively provide disease control with relatively few toxicities, and in certain cases results in a complete response. It is the preferred therapy as a bridge to liver transplant and can provide necessary compensatory future liver remnant hypertrophy before planned surgical resection.

Keywords: (90)Y; Cholangiocarcinoma; Hepatocellular carcinoma; Radiation lobectomy; Radiation segmentectomy; Selective internal radiotherapy (SIRT); Transarterial radioembolization.

Publication types

Review

MeSH terms

Biliary Tract Neoplasms / pathology
Biliary Tract Neoplasms / radiotherapy*
Embolization, Therapeutic / methods*
Humans
Liver Neoplasms / pathology
Liver Neoplasms / radiotherapy*
Prognosis