A novel magnet-based scratch method for standardisation of wound-healing assays

Sci Rep. 2019 Sep 2;9(1):12625. doi: 10.1038/s41598-019-48930-7.


A novel magnetic scratch method achieves repeatability, reproducibility and geometric control greater than pipette scratch assays and closely approximating the precision of cell exclusion assays while inducing the cell injury inherently necessary for wound healing assays. The magnetic scratch is affordable, easily implemented and standardisable and thus may contribute toward better comparability of data generated in different studies and laboratories.

MeSH terms

  • Animals
  • Biological Assay / standards*
  • Cells, Cultured
  • Chondrocytes / cytology
  • Horses
  • Magnetic Phenomena*
  • Reference Standards
  • Wound Healing*