Retiform Purpura: Workup and Therapeutic Considerations in Select Conditions

J Am Acad Dermatol. 2020 Apr;82(4):799-816. doi: 10.1016/j.jaad.2019.07.113. Epub 2019 Aug 31.


In this article we focus on updates in select etiologies of retiform purpura. These causes of retiform purpura, in addition to bacterial or fungal sepsis, disseminated intravascular coagulation, purpura fulminans, and catastrophic antiphospholipid syndrome, are important diagnoses with potential for morbidity and mortality. Important aspects in the pathophysiology, patient demographics and risk factors, updates in the diagnostic workup, histopathology, and treatment of these specific conditions are discussed.

Keywords: ANCA; calciphylaxis; cryoglobulinemia; livedoid vasculopathy; purpura; retiform purpura; vasculitis; vasculopathy.

Publication types

  • Review