Effect of Topical Garlic on Wound Healing and Scarring: A Clinical Trial

Dermatol Surg. 2020 May;46(5):618-627. doi: 10.1097/DSS.0000000000002123.

Abstract

Background: Historically, garlic containing compounds have been used on wounds to improve healing and ward off infection. Researchers have tested many of these ancient ointments, discovering that garlic is a common ingredient in those that are effective.

Objective: To determine the efficacy of topical garlic on surgical wounds compared with Vaseline by analysis of visual analog scales and digital photograph analysis.

Materials and methods: Seventeen patients with 2 skin excisions applied a 30% garlic ointment to one surgical wound and Vaseline to the other surgical wound twice daily. They were followed up at 2 weeks and 4 weeks post-op. Digital photographs were taken of the sites, and wound visual analog scales were filled out by the patient and the physician.

Results: Patients and the onsite physician stated the garlic site healed better in 59% and 65% of the wounds, respectively, at 2 weeks. At 4 weeks, the patients and the onsite physician stated the garlic site healed better in 76% and 88% of wounds, respectively. Digital photograph analysis revealed less erythema at the garlic sites (p-value = .02).

Conclusion: Surgical wounds treated with 30% garlic ointment healed with more cosmetically appealing scars than the Vaseline-treated sites.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Administration, Topical
  • Adult
  • Cicatrix / prevention & control*
  • Esthetics
  • Female
  • Garlic*
  • Humans
  • Male
  • Ointments / administration & dosage*
  • Petrolatum / administration & dosage
  • Photography
  • Skin Diseases / surgery*
  • Wound Healing / drug effects*

Substances

  • Ointments
  • Petrolatum