Pipeline Embolization Device for Treatment of Craniocervical Internal Carotid Artery Dissections: Report of 3 Cases

World Neurosurg. 2019 Dec:132:106-112. doi: 10.1016/j.wneu.2019.08.183. Epub 2019 Sep 3.

Abstract

Background: Dissecting pseudoaneurysms of the craniocervical circulation are uncommon, accounting for only 3% of all cerebral aneurysms. These aneurysms pose a challenge due to their location and anatomic configuration. The Pipeline Embolization Device (PED) is a flow diversion technique that successfully treats aneurysms by diverting blood flow away from the aneurysm and reconstructing the diseased parent artery by altering its hemodynamics.

Case description: We report 3 cases in which the PED was used to treat craniocervical carotid artery dissection with associated pseudoaneurysms. A single PED was used in the first case, 4 PEDs were used in the second case, and 3 PEDs and a PRECISE PRO RX carotid stent were placed in the third case. All 3 patients achieved full neurologic recovery postoperatively. Cerebral angiography performed postoperatively demonstrated revascularization, good laminar flow, and no in-stent or adjacent stenosis.

Conclusions: PED placement offers a safe and effective method of treating spontaneous or traumatic craniocervical carotid artery dissections with excellent neurologic outcomes postoperatively and complete long-term aneurysmal occlusion.

Keywords: Aneurysm; Carotid artery; Dissection; Endovascular; Neurosurgery; Pipeline Embolization Device.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aneurysm, False / complications
  • Aneurysm, False / diagnostic imaging
  • Aneurysm, False / therapy*
  • Angiography, Digital Subtraction
  • Carotid Artery Diseases / complications
  • Carotid Artery Diseases / diagnostic imaging
  • Carotid Artery Diseases / therapy
  • Carotid Artery, Internal, Dissection / complications
  • Carotid Artery, Internal, Dissection / diagnostic imaging
  • Carotid Artery, Internal, Dissection / therapy*
  • Cerebral Angiography
  • Computed Tomography Angiography
  • Embolization, Therapeutic / instrumentation*
  • Embolization, Therapeutic / methods
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male