Stress due to earthquakes and other natural catastrophic events may result in a decline in the male to female ratio of newborn infants. One reason may be an increased death of male fetuses 3-5 months earlier. Another reason may relate to reduced conception of males and/or early male embryo demise 8-10 months earlier. Almost all of the earthquakes and natural catastrophic events have caused declines in sex ratios at birth except the Hurricane Katrina which showed a rise in the birth sex ratio. We describe hypothetical immunological cause for the decline in the sex ratio at birth following periods of augmented stress levels.
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