Impact of fluorescence and autofluorescence on surgical strategy in benign and malignant neck endocrine diseases

Best Pract Res Clin Endocrinol Metab. 2019 Aug;33(4):101311. doi: 10.1016/j.beem.2019.101311. Epub 2019 Aug 10.


Fluorescence and autofluorescence have been shown by several recent studies to be valuable adjuncts in identifying parathyroid glands during thyroidectomy and parathyroidectomy. The aim of this chapter is to review the impact of this new technology on surgical strategy concerning identification and preservation of parathyroid glands during thyroidectomy, identification of parathyroid glands in hyperparathyroidism, and the potential role in thyroid cancer surgery.

Keywords: autofluorescence; indocyanine green; near-infrared; parathyroid gland; thyroid gland.

Publication types

  • Review

MeSH terms

  • Fluorescence
  • Fluorescent Dyes / adverse effects*
  • Humans
  • Optical Imaging / methods*
  • Parathyroid Neoplasms / surgery*
  • Parathyroidectomy / methods*
  • Thyroid Neoplasms / surgery*
  • Thyroidectomy / methods*


  • Fluorescent Dyes