Bisphenol A Analogues in Food and Their Hormonal and Obesogenic Effects: A Review

Nutrients. 2019 Sep 6;11(9):2136. doi: 10.3390/nu11092136.


Bisphenol A (BPA) is the most well-known compound from the bisphenol family. As BPA has recently come under pressure, it is being replaced by compounds very similar in structure, but data on the occurrence of these BPA analogues in food and human matrices are limited. The main objective of this work was to investigate human exposure to BPA and analogues and the associated health effects. We performed a literature review of the available research made in humans, in in vivo and in vitro tests. The findings support the idea that exposure to BPA analogues may have an impact on human health, especially in terms of obesity and other adverse health effects in children.

Keywords: bisphenol A analogues; food; obesogenic effect.

Publication types

  • Systematic Review

MeSH terms

  • Adipose Tissue / drug effects*
  • Adipose Tissue / metabolism
  • Adipose Tissue / physiopathology
  • Adiposity / drug effects*
  • Animals
  • Benzhydryl Compounds / adverse effects*
  • Benzhydryl Compounds / analysis
  • Endocrine Disruptors / adverse effects*
  • Endocrine Disruptors / analysis
  • Energy Metabolism / drug effects*
  • Food Contamination*
  • Humans
  • Obesity / chemically induced*
  • Obesity / metabolism
  • Obesity / physiopathology
  • Phenols / adverse effects*
  • Phenols / analysis
  • Risk Assessment
  • Risk Factors


  • Benzhydryl Compounds
  • Endocrine Disruptors
  • Phenols
  • bisphenol A