Recurrence of group B streptococcal meningitis

Arch Pediatr. 2019 Sep;26(6):374-376. doi: 10.1016/j.arcped.2019.08.003. Epub 2019 Sep 8.


Group B Streptococcus is the most frequent cause of neonatal sepsis. However, recurrences are rare. We report a case of recurrent meningitis due to Streptococcus B in a 2-month-old infant. Streptococcus B identified was hypervirulent clone ST-17 serotype III, which is known for its neurotropism. We found five other cases of recurrent group B streptococcal meningitis in the literature, which we report here. Many reports have identified breastfeeding and persistent colonization as the mode of transmission in recurrent Streptococcus B infections. We also discuss different ways to prevent recurrent group B streptococcal infections. Oral antibiotic therapy against carriage does not seem to be effective and there is no consensus on management of breastfeeding.

Keywords: Group B Streptococcus; Meningitis; Recurrent infection.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Female
  • Humans
  • Infant
  • Meningitis, Bacterial / diagnosis*
  • Meningitis, Bacterial / drug therapy
  • Recurrence
  • Streptococcal Infections / diagnosis*
  • Streptococcal Infections / drug therapy
  • Streptococcus agalactiae / isolation & purification*


  • Anti-Bacterial Agents