Building Blastocysts from Stem Cells

Stem Cell Reports. 2019 Sep 10;13(3):437-439. doi: 10.1016/j.stemcr.2019.08.009.


The blastocyst stage and the subsequent implantation are critical for a successful pregnancy, yet are challenging to study in vivo. In this issue of Stem Cell Reports, Kime et al. (2019) describe a novel way to generate blastocyst-like structures only from pluripotent stem cells. These structures mimic several aspects of the early embryo, offering a new promising tool to study this stage.

Publication types

  • Comment

MeSH terms

  • Blastocyst*
  • Embryo Implantation*
  • Female
  • Humans
  • Pregnancy
  • Stem Cells