A case report on anti-Mia antibody in a multi-transfused patient from India

Transfus Apher Sci. 2019 Oct;58(5):625-627. doi: 10.1016/j.transci.2019.08.027. Epub 2019 Sep 5.

Abstract

GP.Mur antigen belongs to the MNSs system and the corresponding antibody is called as anti-Mia antibody. Anti-Mia antibody is a clinically significant antibody capable of causing haemolytic disease of the new born (HDFN) and intravascular haemolytic transfusion reactions. Literature on anti-Mia antibody from India is very limited. We report here a case of anti-Mia antibody in a multi-transfused patient from India.

Keywords: Anti-Mia; Mia antigen; Miltenberger series.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Blood Group Antigens* / blood
  • Blood Group Antigens* / immunology
  • Erythrocyte Transfusion / adverse effects*
  • Glycophorins* / blood
  • Glycophorins* / immunology
  • Humans
  • India
  • Isoantibodies* / blood
  • Isoantibodies* / immunology
  • Male
  • beta-Thalassemia* / blood
  • beta-Thalassemia* / immunology
  • beta-Thalassemia* / therapy

Substances

  • Blood Group Antigens
  • Glycophorins
  • Isoantibodies
  • Miltenberger III-like molecule glycophorin variant