Metastatic Bilateral Strumal Carcinoid: A Case Report and Review of the Literature

Anticancer Res. 2019 Sep;39(9):5053-5056. doi: 10.21873/anticanres.13697.


Primary ovarian carcinoids are very rare tumors that belong to the germ cell family of ovarian malignancies. They account for less than 1% of all carcinoid tumors and for less than 0.1% of all ovarian neoplasms. Recurrences are even rarer, with only few cases reported in the literature. Strumal carcinoid has recently been recognized as an extremely rare distinct entity. We report on a patient with bilateral mature cystic teratoma with millimetric foci of ovarian strumal carcinoid who developed lymph node para aortic metastasis after 30 years from primary diagnosis. Our case is thus far the second report of a metastatic strumal carcinoid and the first one in which strumal carcinoid occurred bilaterally and was also metastatic.

Keywords: IOTA simple rules; Strumal carcinoid; bilateral mature cystic teratoma; lymph node metastasis; malignant strumal carcinoid; neuroendocrine tumor; ovary; primary ovarian carcinoid.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Biopsy
  • Carcinoid Tumor / diagnosis*
  • Carcinoid Tumor / therapy
  • Combined Modality Therapy
  • Female
  • Humans
  • Middle Aged
  • Neoplasm Metastasis
  • Neoplasm Staging
  • Ovarian Neoplasms / diagnosis*
  • Ovarian Neoplasms / therapy
  • Positron Emission Tomography Computed Tomography
  • Struma Ovarii / diagnosis*
  • Struma Ovarii / therapy
  • Tomography, X-Ray Computed