Effects of progressive muscle relaxation and mindfulness meditation on fatigue, coping styles, and quality of life in early breast cancer patients: An assessor blinded, three-arm, randomized controlled trial

Eur J Oncol Nurs. 2019 Oct;42:116-125. doi: 10.1016/j.ejon.2019.09.003. Epub 2019 Sep 6.

Abstract

Purpose: This study aimed to investigate the effects of progressive muscle relaxation (PMR) and mindfulness meditation (MM) on fatigue, coping styles, and quality of life (QOL) in patients with early breast cancer receiving adjuvant paclitaxel.

Methods: The participants were randomly assigned to either a 12-week (PMR) (n = 31) and MM (n = 32) interventions or control group (CG) (n = 29). The intervention groups continued PMR or MM for 20-min every day, for a total of 12 weeks. The CG received only a single time attention-matched education (15-min) on breast cancer before the start of the paclitaxel regimen. Data collection tools included the Patient Information Form, Brief Fatigue Inventory (BFI), Brief COPE, and Functional Living Index-Cancer (FLIC). Data were collected at baseline, week 12, and week 14.

Results: A significant reduction in the BFI scores was reported in the PMR and MM groups when compared with the CG at weeks 12 and 14 (p = .002). Similarly, the use of emotional support and positive reframing sub-dimension scores of Brief COPE were significantly higher in the PMR and MM than in the CG at weeks 12 (p = .017) and 14 (p = .042). Furthermore, the planning and active coping sub-dimension scores were significantly higher in the PMR and MM than in the CG at week 14 (p = .000). Regarding QOL scores, no significant differences were observed between the groups at weeks 12 (p = .486) and 14 (p = .095).

Conclusions: PMR and MM are effective interventions that if initiated concurrently with the adjuvant paclitaxel demonstrate similar effects on fatigue and coping styles.

Keywords: Breast cancer; Coping style; Fatigue; Meditation; Quality of life; Relaxation.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adaptation, Psychological*
  • Adult
  • Autogenic Training*
  • Breast Neoplasms / pathology
  • Breast Neoplasms / psychology*
  • Breast Neoplasms / therapy
  • Fatigue / etiology
  • Fatigue / therapy*
  • Female
  • Humans
  • Meditation*
  • Middle Aged
  • Mindfulness
  • Quality of Life*