Neurosarcoidosis Presenting as Isolated Bilateral Cerebellopontine Angle Tumors: Case Report and Review of the Literature

Ear Nose Throat J. 2019 Sep;98(8):NP120-NP124. doi: 10.1177/0145561319860528.


Objectives: To describe a unique case of isolated bilateral sarcoidosis of the cerebellopontine angle as well as the related imaging in the case. To conduct a literature review of the published articles regarding sarcoidosis of the cerebellopontine angle.

Data sources: Representative case report from a single institution as well as PubMed and Scopus database searches.

Methods: In addition to a retrospective review, all published case reports and case series of sarcoidosis involving the cerebellopontine angle from 1960 to July 2018 in the English language were reviewed. Demographic data, presenting symptoms, and outcomes were collected.

Results: We identified 8 total cases with pertinent clinical information that were included.

Conclusions: Isolated neurosarcoidosis of the cerebellopontine angle is an exceptionally rare phenomenon that, on history and imaging, presents similar to more common retrocochlear pathologies. Surgery may be required in large lesions unresponsive to traditional medical therapy with immunosuppression.

Keywords: cerebellopontine angle tumor; intracranial granuloma; neurosarcoidosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Central Nervous System Diseases / diagnostic imaging*
  • Central Nervous System Diseases / pathology*
  • Central Nervous System Diseases / surgery
  • Diagnosis, Differential
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Neuroma, Acoustic / diagnostic imaging*
  • Sarcoidosis / diagnostic imaging*
  • Sarcoidosis / pathology*
  • Sarcoidosis / surgery

Supplementary concepts

  • Neurosarcoidosis