Ranibizumab and Aflibercept Levels in Breast Milk after Intravitreal Injection

Ophthalmology. 2020 Feb;127(2):278-280. doi: 10.1016/j.ophtha.2019.08.022. Epub 2019 Sep 12.

Authors

Verena R Juncal¹, Quratulain Paracha², Motaz Bamakrid², Carolina L M Francisconi¹, Julia Farah³, Amin Kherani⁴, Rajeev H Muni⁵

Affiliations

¹ Department of Ophthalmology, St. Michael's Hospital, Toronto, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada.
² Department of Ophthalmology, St. Michael's Hospital, Toronto, Canada.
³ Department of Ophthalmology, University of Calgary, Calgary, Canada.
⁴ Department of Ophthalmology, University of Calgary, Calgary, Canada; Calgary Retina Consultants, Calgary, Canada.
⁵ Department of Ophthalmology, St. Michael's Hospital, Toronto, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada; Department of Ophthalmology, The Hospital for Sick Children, Toronto, Canada; Kensington Vision and Research Centre, Toronto, Canada. Electronic address: rajeev.muni@gmail.com.

PMID: 31526521
DOI: 10.1016/j.ophtha.2019.08.022

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Angiogenesis Inhibitors / administration & dosage
Angiogenesis Inhibitors / metabolism*
Choroidal Neovascularization / drug therapy
Diabetic Retinopathy / drug therapy
Enzyme-Linked Immunosorbent Assay
Female
Humans
Intravitreal Injections
Macular Edema / drug therapy
Milk, Human / metabolism*
Myopia, Degenerative / drug therapy
Ranibizumab / administration & dosage
Ranibizumab / metabolism*
Receptors, Vascular Endothelial Growth Factor / administration & dosage
Receptors, Vascular Endothelial Growth Factor / metabolism*
Recombinant Fusion Proteins / administration & dosage
Recombinant Fusion Proteins / metabolism*
Vascular Endothelial Growth Factor A / antagonists & inhibitors
Young Adult

Substances

Angiogenesis Inhibitors
Recombinant Fusion Proteins
VEGFA protein, human
Vascular Endothelial Growth Factor A
aflibercept
Receptors, Vascular Endothelial Growth Factor
Ranibizumab